Liangliang Gao is a post-doctoral Research Associate in bioinformatics, working in Dr. Jesse Poland’s group at Kansas State University. Dr. Gao joined the Poland Lab in Aug 2016 and his main research goal is to lead computational approaches to utilize next generation sequencing data for genomics-assisted breeding in wheat. Dr. Gao is developing improved approaches for analysis of genotyping by sequencing (GBS) data and whole genome sequence data for genome anchoring and translate genomic information to prediction models for genomic selection.
As of June 2017, Dr. Gao mainly worked on three projects at the Poland lab:
- 1) Validating the Chinese Spring wheat reference genome assembly using de novo GBS maps and physical BAC sequences of wheat chromosomes 1D, 4D, 6D and 3A
- 2) Identification of an alien wheat fragment (Aegilops ventricosa 2NS) in Kansas wheat breeding lines and preliminary 2NS-yield relationships analysis
- 3) Generating a draft and ordered genome sequence for winter wheat cultivar Jagger using chromosome conformation capture and massively parallel sequencing (Hi-C)
Dr. Gao’s research projects at the Poland lab might also include developing novel genotyping assays for wheat, pan genome analysis in wheat, and potentially Hi-C genome anchoring for intermediate wheatgrass.
Dr. Gao published nine journal articles, one book chapter and over 12 abstracts for scientific conferences (google scholar profile: https://scholar.google.com/citations?user=ZSvjo8kAAAAJ&hl=en). Dr. Gao’s previous research focused on organ specific defense against late blight in potato, mapping wheat genes effective to rust diseases, genome wide association study of wheat disease resistance traits, and genomic selections in wheat scab resistance. Dr. Gao also served as a reviewer for 19 pre-publication journal articles (Journal review profile: https://publons.com/author/422237/liangliang-gao#profile). Dr. Gao actively develops novel and efficient computer programs or pipelines to automate crop science data conversion (Github site: https://github.com/umngao)
Ph.D. Plant Pathology (Potato Pathology & Genomics), University of Minnesota | 2013
M.S. Crop Genetics and Breeding, China Agricultural University, Beijing, China | 2007
B.S. Biological Science, Hebei University, Baoding, China | 2004
Gao, L., Rouse, M. N., Mihalyov, P. D., Bulli, P., Pumphrey M. O. and Anderson, J. A. (2017) Genetic Characterization of Stem Rust Resistance in a Global Spring Wheat Germplasm Collection. Crop Science (in press)
Gao, L., and Bradeen, J. M. 2016. Contrasting Potato Foliage and Tuber Defense Mechanisms against the Late Blight Pathogen Phytophthora infestans. PLoS One 11:e0159969.
Gao, L., Turner, M. K., Chao, X. M., Kolmer J., Anderson J. A. (2016) Genome wide association study (GWAS) of seedling and adult plant leaf rust resistance in elite wheat breeding lines PLoS One DOI:10.1371/journal.pone.0148671
Zhang, X., Sallam, A., Gao, L., Kantarski, T., Poland, J., DeHaan, L. R., Wyse, D. and Anderson, J. A. (2016) Establishment and optimization of genomic selection to accelerate the domestication and improvement of intermediate wheatgrass (Thinopyrum intermedium) using recurrent selection. The Plant Genome DOI: 10.3835/plantgenome2015.07.0059 (https://dl.sciencesocieties.org/publications/tpg/abstracts/0/0/plantgenome2015.07.0059)
Gao, L., Kielsmeier-Cook, J., Bajgain, P., Zhang, X., Chao, S., Rouse, M. N. and Anderson, J. A. (2015) Development of genotyping by sequencing (GBS)- and array-derived SNP markers for stem rust resistance gene Sr42. Molecular Breeding 35:207 (http://link.springer.com/article/10.1007%2Fs11032-015-0404-4)
Millett, B., Gao. L. (co-first author), Iorizzo1 M., Carputo D., Bradeen J.M.(2015) Potato tuber blight resistance phenotypes correlate with RB transgene transcript levels in an age-dependent manner. Phytopathology 105:1131-1136 (http://apsjournals.apsnet.org/doi/10.1094/PHYTO-10-14-0291-R)
Iorizzo, M., Gao, L. (co-first author), Mann, H., Chiusano, M.L., Carputo, D., Kilian A., Bradeen, J.M. (2014) A DArT marker-based linkage map for wild potato Solanum bulbocastanum facilitates structural comparisons between Solanum A and B genomes. BMC genetics 15:123 (http://www.biomedcentral.com/1471-2156/15/123)
Zhou, P., Silverstein K.A.T., Gao, L., Nallu, S., Guhlin J. and Young, N.D. (2013) Detecting Small Plant Peptides in Plants using SPADA (Small Peptide Alignment Discovery Application). BMC Bioinformatics 14:335 (http://www.biomedcentral.com/1471-2105/14/335)
Gao, L., Tu, Z.J., Millett B., Bradeen, J.M. (2013) Insights into organ-specific pathogen defense responses in plants: RNA-seq analysis of potato tuber-Phytophthora infestans interactions. BMC Genomics 14:340 (http://www.biomedcentral.com/1471-2164/14/340)