New paper in BMC Genomics that presents spiked GBS, which combines targeted amplicon sequencing with reduced representation genotyping-by-sequencing. To reduce the cost of targeted assays, we use a small percent of sequencing capacity available in runs of GBS libraries to “spike” amplified targets tagged with a different set of unique barcodes. This open platform will allow multiple, single-target loci to be assayed while simultaneously generating a whole-genome profile.
New perspective paper on genomics and plant breeding is out in Current Opinion in Plant Biology. Breeding assisted genomics is the concept of shifting effort for basic genomic studies from dedicated structured populations, to capturing the entire scope of genetic determinants in breeding lines. By doing this we can move towards not only furthering our understanding of functional genomics in plants, but also rapidly improving crops for increased food security, availability and nutrition.